Weight Loss Medication vs

Bariatric Surgery

What Studies Tell Us

  • Diet/exercise study results: 1 in 4 gained weight, 1 in 4 lost less than 5%, and 2 in 4 lost more than 5%.

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    Diet & Lifestyle

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  • Illustration of weight loss outcomes after stopping semaglutide. People grouped with percentages kept off starting weight.

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    Weight Loss Medications

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  • Infographic on bariatric surgery weight loss outcomes, with a group of people and percentage statistics.

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    Bariatric Surgery

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What early results say:

  • Graph showing weight change over 5 years after diet and exercise, with varied weight regain among study participants.

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    After Lifestyle & Diet

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  • Graph showing weight changes after stopping GLP-1 injections, with significant weight regain over time.

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    After Weight Loss Medications

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  • Graph showing weight loss and regain after bariatric surgery. Percentage changes over 10 years are charted.

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    After Bariatric Surgery

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Individual results vary. Risks and benefits of each treatment should be discussed with a doctor.

† Variation comes from different surgery procedures. Less than 1 in 20 people had <5% total weight loss 5 years after Roux-in-y Gastric Bypass.. However, for Sleeve Gastrectomy patients 2 in 20 had <5%TWL 5 years after surgery.

‡ Variation comes from different surgery procedures. !6 out of 20 sleeve gastrectomy patients maintained >20% total weight loss 5 years after surgery. 18 out 20 roux-en-y gastric bypass patients maintained >20% TWL 5 years after surgery. N=919. 


1) Look Ahead research group. Eight year weight losses with an intensive lifestyle intervention: the look Ahead study. Obesity. 2014. 2) Wilding, Batterham et al. Step Trial Extension. 3) Rubino et al. Step 4. 4) Tettero OM, Monpellier VM, Janssen MC et al. Early postpoperative weight loss predicts weight loss up to 5 years after roux-en-y gastric bypass, banded roux-en-y gastric bypass, and sleeve gastrectomy. Obesity Surgery. 2022. doi.org/10.1007/s11695-022-06166-x 5) 6) Internal analysis of the difference between <5% and >20% TWL 5 years post-op. 2023. 7) Sanchez-Cordero, Sergi t al. Analysis of the variability in different criteria to define the success of bariatric surgery: retrospective study 5-year follow-up after Sleeve Gastrectomy and Roux-en-Y Gastric Bypass. J clin Med. 2023. doi: 10.3390/jcm12010187